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Patients are advised to: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or spicy foods that may exacerbate nausea Stay well hydrated, taking small sips of water throughout the day Avoid lying down immediately after eating Identify and avoid personal trigger foods Timing and administration are crucial for optimal tolerability

Analysis of tissue samples found that GLP-1 receptor proteins were most numerous in the pancreas, consistent with the drugs' known benefits in diabetes, but the heart had the second-highest concentration

This, if true, would be very different from earlier drugs in this class, where roughly 25 to 40% of the weight lost tends to come from lean mass

Y., & Fernandez, M